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KMID : 0191120120270040446
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Journal of Korean Medical Science
2012 Volume.27 No. 4 p.446 ~ p.449
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Immunoglobulin A Nephropathy Associated with Plasmodium falciparum Malaria
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Yoo Dong-Eun
Kim Jeong-Ho
Kie Jeong-Hae
Park Yoon-Seon
Chang Tae-Ik
Oh Hyung-Jung
Kim Seung-Jun
Yoo Tae-Hyun
Choi Kyu-Hun
Kang Shin-Wook
Han Seung-Hyeok
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Abstract
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Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laboratory tests after recovery from malaria showed disappearance of urinary abnormalities and normalization of kidney function. Our findings suggest that malaria infection might be associated with IgA nephropathy.
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KEYWORD
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Glomerulonephritis, IgA nephropathy, Malaria, Plasmodium falciparum
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